Whenever proportional parts enter into a calculation, reduce them to lowest terms. It is much easier to solve using a decimal or percent, like 10 (%) : 0.2 (%) than a fraction represented by the ratio like 1⁄10 : 1⁄500. When ratio strengths are given, convert them to percentage strengths before setting up a proportion. These two rules, wherever they may be applied, greatly simplify the calculation: 1. The best way is not necessarily the shortest: the best way is the one that is clearly understood and that leads to the correct answer. Many problems can be solved in several ways. Understanding the basic concepts of dilution and concentration uncomplicates these problems.
#How to do dilution series math 3ml series#
Solving some of these calculations requires a series of steps. Problems such as these sometimes seem complicated and difficult. Pharmaceutical preparation after dilution (same amount of active drug although the volume has doubled) Pharmaceutical preparation before dilution This chapter introduces problems of a slightly different character: those that arise when pharmaceutical preparations are diluted (by the addition of diluent or by admixture with solutions or mixtures of lower strength) or are concentrated (by the addition of active ingredient or by admixture with solutions or mixtures of greater strength). A diluent most often has no drug substance in it examples are sterile water and petrolatum.Ĭhapter 9 addresses problems arising from the quantitative relationship between specific ingredients and the pharmaceutical preparation as a whole. Pharmaceutical Calculations for the Pharmacy Technicianĭiluent A substance added to a pharmaceutical product to reduce its strength, or dilute it. Use the alligation methods (alligation alternate and alligation medial) to determine relative amounts of components mixed together to make a mixture of a required strength.
Use the alligation methods (alligation alternate and alligation medial) to determine the percent strength of alcohol mixtures.Define the alligation methods of problem solving.Determine the quantity of an active ingredient in a specified amount of solution needed to prepare a given solution.Determine the volume of a specified stock solution needed to prepare a given solution.Determine the volume of solution of a desired strength given a specified quantity of any given strength.Determine the percent strength and ratio strength of a given product when the active ingredient remains constant and the amount of diluent is increased or decreased.Describe the relationship of active ingredients and diluents if the amount of active ingredient remains constant and the amount of diluent is increased or decreased.Dilution and Concentration OBJECTIVES Upon completion of this chapter, the technician student will be able to: